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2013, Cilt 4, Sayı 4, Sayfa(lar) 220-222
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Hepatoid Adenocarcinoma in Gallbladder: A Case Report
Mustafa Yıldırım1, Cem Parlak2, Mustafa Yıldız3, Nurullah Bülbüller4, Cem Sezer5, Çağlar Yıldırım4, Çetin Kaya3, Elif Peştereli6
1Batman Regional Goverment Hospital, Department of Medical Oncology, Batman, Türkiye
2Başkent Universty Faculty of Medicine, Department of Radiation Oncology, Antalya, Türkiye
3Antalya Education and Research Hospital, Department of Medical Oncology, Antalya, Türkiye
4Antalya Education and Research Hospital, Department of Surgery, Antalya, Türkiye
5Antalya Education and Research Hospital, Department of Pathology, Antalya, Türkiye
6Akdeniz University Faculty of Medicine , Department of Pathology, Antalya, Türkiye
Keywords: gallbladder, hepatoid adenocarcinoma, ovary, metastasis
Abstract
Hepatoid adenocarcinoma is a rare extrahepatic tumor, resembling hepatocellular carcinoma. It resembles hepatocytes both morphologically and functionally. Serum level of AFP is high in most cases. They reveal positive immunostaining with AFP, CEA, CK-8 and CK-18. To make the diagnosis of Hepatoid adenocarcinoma, hepatocellular carcinoma should be ruled out. Although it has an aggressive natural history, some cases like ours may show slower course, and recur in distant sites. In this article, we present a case of ovarian Hepatoid adenocarcinoma who presented with tumor in gallbladder having similar histopathology after 3 years of initial diagnosis.
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