Lichen planus is a lymphocytic inflammatory disorder of unknown
origin mediated by cellular immunity. The reports documenting contact
hypersensitivity to certain antigens are increasing in number mainly in
oral but also in cutaneous lichen planus as well. However, there are only a
few studies questioning whether there is any alteration in contact hypersensitivity
response in this patient group due to T-cell mediated changes.
Methods: The purpose of this study is to find out the prevalence of contact
hypersensitivity to standard contact allergens in cutaneous lichen planus
patients. In the present study 43 cutaneous lichen planus patients and 33
controls were patch tested by T.R.U.E test methodology.
Resulst: A positive patch test reaction was found in 11.6% of the lichen
planus patients while the control group showed a percentage of 30.3%.
Statistically, the difference between the two groups was not significant
(Fischer test p=0.07).
Conclusions: This is the first study examining into the standard patch test
positivity in cutaneous lichen planus patients the results showed no difference
from the control.