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2015, Cilt 6, Sayı 1, Sayfa(lar) 052-054
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Prothrombin Gene Mutation as a Risk Factor in Young Ischemic Stroke: A Case Report
Dilcan Kotan1, Lütfi Özel2, Hızır Ulvi2, Recep Aygül2
1Sakarya Üniversitesi Tıp Fakültesi, Nöroloji, Sakarya, Türkiye
2Atatürk Üniversitesi Tıp Fakültesi, Nöroloji, Erzurum, Türkiye
Keywords: young stroke, prothrombin gene mutation, pregnancy
Abstract
Stroke at young age is the stroke seen under the age of 45 years with the incidence range between 2.5 and 40/100.000. Stroke at young age is account for 4-10% of overall stroke cases. The majority of strokes in young adults are of ischemic origin. The causes of young ischemic strokes are different than those of advanced age and many analyses may be required to find out the underlying reason. These analyses include cerebral angiography, transesophageal echocardiography, tests to detect coagulation disorders, and investigation of collagen vascular diseases. Studies have most frequently focused on FV Leiden, MTHFR C677T and Prothrombin G20210A, which are among prothrombotic gene mutations in thrombophilia panel. Herein, a young female case with young ischemic stroke, in which heterozygote polymorphism of prothrombotic gene has been detected, was presented.
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